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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TNK1
All Species:
1.52
Human Site:
T458
Identified Species:
3.33
UniProt:
Q13470
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13470
NP_003976.2
666
72468
T458
T
R
P
V
H
R
G
T
P
A
R
G
D
Q
H
Chimpanzee
Pan troglodytes
XP_511968
661
71812
D458
R
G
T
P
A
R
G
D
Q
H
P
G
S
I
D
Rhesus Macaque
Macaca mulatta
XP_001107819
661
71894
D458
R
G
T
P
A
R
G
D
Q
H
P
G
N
I
D
Dog
Lupus familis
XP_546588
759
83022
G538
R
V
F
P
P
A
Q
G
E
R
R
Q
G
N
I
Cat
Felis silvestris
Mouse
Mus musculus
Q99ML2
666
73081
E459
R
G
S
P
A
H
G
E
K
C
R
G
G
T
D
Rat
Rattus norvegicus
Q5U2X5
1040
115050
G466
Q
N
S
F
I
H
T
G
H
G
D
S
D
P
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q00944
1053
119189
A757
S
H
G
I
P
A
M
A
G
S
I
Y
P
G
Q
Frog
Xenopus laevis
Q91738
1068
121137
S770
A
H
G
I
P
S
M
S
G
N
M
Y
P
G
Q
Zebra Danio
Brachydanio rerio
NP_001073486
732
83488
S447
I
S
S
P
V
R
G
S
L
H
H
T
G
H
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9I7F7
1337
147458
R477
F
S
R
V
S
D
H
R
I
S
K
R
K
L
R
Honey Bee
Apis mellifera
XP_396503
1302
145297
H448
P
L
E
N
S
F
I
H
T
G
H
G
A
P
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98
96
74.4
N.A.
82.7
30.3
N.A.
N.A.
21.1
21
39.6
N.A.
21.3
23.7
N.A.
N.A.
Protein Similarity:
100
98.1
97.3
78.5
N.A.
87.5
40.9
N.A.
N.A.
34.8
34.2
55.1
N.A.
31.5
33.7
N.A.
N.A.
P-Site Identity:
100
20
20
6.6
N.A.
20
6.6
N.A.
N.A.
0
0
13.3
N.A.
6.6
6.6
N.A.
N.A.
P-Site Similarity:
100
20
26.6
6.6
N.A.
20
6.6
N.A.
N.A.
20
13.3
20
N.A.
20
6.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
28
19
0
10
0
10
0
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
10
0
19
0
0
10
0
19
0
28
% D
% Glu:
0
0
10
0
0
0
0
10
10
0
0
0
0
0
0
% E
% Phe:
10
0
10
10
0
10
0
0
0
0
0
0
0
0
10
% F
% Gly:
0
28
19
0
0
0
46
19
19
19
0
46
28
19
10
% G
% His:
0
19
0
0
10
19
10
10
10
28
19
0
0
10
10
% H
% Ile:
10
0
0
19
10
0
10
0
10
0
10
0
0
19
10
% I
% Lys:
0
0
0
0
0
0
0
0
10
0
10
0
10
0
0
% K
% Leu:
0
10
0
0
0
0
0
0
10
0
0
0
0
10
0
% L
% Met:
0
0
0
0
0
0
19
0
0
0
10
0
0
0
0
% M
% Asn:
0
10
0
10
0
0
0
0
0
10
0
0
10
10
0
% N
% Pro:
10
0
10
46
28
0
0
0
10
0
19
0
19
19
0
% P
% Gln:
10
0
0
0
0
0
10
0
19
0
0
10
0
10
19
% Q
% Arg:
37
10
10
0
0
37
0
10
0
10
28
10
0
0
19
% R
% Ser:
10
19
28
0
19
10
0
19
0
19
0
10
10
0
0
% S
% Thr:
10
0
19
0
0
0
10
10
10
0
0
10
0
10
0
% T
% Val:
0
10
0
19
10
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
19
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _